Astroglial cells were long considered as structural and metabolic supporting cells are which
do not directly participate in information processing in the brain. Discoveries of …

Alzheimer's disease (AD) is an age-related dementia and neurodegenerative disorder,
characterized by Aβ and tau protein deposition impairing learning, memory and suppressing …

It has been suggested that exercise training and probiotic supplementation could decelerate
the progress of functional and biochemical deterioration in APP/PS1 transgenic mice …

N-acetyl-aspartyl-glutamate (NAAG) is the most abundant dipeptide in the brain, where it
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …

Neurodegenerative disorders are characterized by excitotoxicity and neuroinflammation that
finally lead to slow neuronal degeneration and death. Although neurons are the principal …

Glutamate is a major excitatory neurotransmitter in the central nervous system (CNS) and
abnormalities in the glutamatergic system underlie various CNS disorders. As metabotropic …

Glutamate, the major excitatory neurotransmitter in the brain exerts its effects via both
ionotropic glutamate receptors and metabotropic glutamate receptors (mGluRs). There are …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
impairment of cognition, memory deficits and behavioral abnormalities. Accumulation of …

Astrocytes are well known to play critical roles in the development and maintenance of the
central nervous system (CNS). Moreover, recent reports indicate that these cells are …

Microglia play a vital role in maintaining brain homeostasis. Their continuous sensing of
surrounding micro‐environments is crucial for their activity. Cross talk between specific …