Oxidative stress and reactive oxygen species: a review of their role in ocular disease

L Ung, U Pattamatta, N Carnt… - Clinical …, 2017 - portlandpress.com
For many years, oxidative stress arising from the ubiquitous production of reactive oxygen
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …

Behçet's disease–a contemporary review

D Mendes, M Correia, M Barbedo, T Vaio, M Mota… - Journal of …, 2009 - Elsevier
Behçet's disease (BD) is a systemic vasculitis disorder of unknown etiology, characterized
by relapsing episodes of oral aphthous ulcers, genital ulcers, skin lesions and ocular …

2018 update of the EULAR recommendations for the management of Behçet's syndrome

G Hatemi, R Christensen, D Bang, B Bodaghi… - Annals of the …, 2018 - ard.bmj.com
Several new treatment modalities with different mechanisms of action have been studied in
patients with Behçet's syndrome (BS). The aim of the current effort was to update the …

EULAR recommendations for the management of Behçet disease

G Hatemi, A Silman, D Bang, B Bodaghi… - Annals of the …, 2008 - ard.bmj.com
Objectives: To develop evidence-based European League Against Rheumatism (EULAR)
recommendations for the management of Behçet disease (BD) supplemented where …

Efficacy of anti-TNF alpha in severe and/or refractory Behçet's disease: multicenter study of 124 patients

H Vallet, S Riviere, A Sanna, A Deroux, G Moulis… - Journal of …, 2015 - Elsevier
Objective To report the efficacy and safety of anti-TNF agents in patients with severe and/or
refractory manifestations of Behçet's disease (BD). Methods We performed a multicenter …

Anti-TNF agents for Behçet's disease: analysis of published data on 369 patients

A Arida, K Fragiadaki, E Giavri, PP Sfikakis - Seminars in arthritis and …, 2011 - Elsevier
OBJECTIVE:: Off-label use of anti-tumor necrosis factor (TNF) agents for Behçet's disease
(BD) is increasing. We evaluated published data on their efficacy and safety for patients with …

The first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directions

PP Sfikakis - TNF pathophysiology, 2010 - karger.com
Results from clinical trials of biologic anti-TNF drugs performed in the late 1990s confirmed
the biological relevance of TNF function in the pathogenesis of chronic noninfectious …

Behçet's syndrome: disease manifestations, management, and advances in treatment

H Yazici, I Fresko, S Yurdakul - Nature clinical practice Rheumatology, 2007 - nature.com
The acne lesions characteristic of Behçet's syndrome are not sterile and are commonly
observed in combination with arthritis. The two main nodular skin lesions—superficial …

Adalimumab in the therapy of uveitis in childhood

S Biester, C Deuter, H Michels, R Haefner… - British Journal of …, 2007 - bjo.bmj.com
Purpose: Chronic anterior uveitis in children often takes a serious course. Despite various
immunosuppressive drugs some children do not respond sufficiently and there is a high risk …

Anti-TNF therapy in the management of Behçet's disease—review and basis for recommendations

PP Sfikakis, N Markomichelakis, E Alpsoy… - …, 2007 - academic.oup.com
Behcet's disease (BD) is a multisystem, chronic-relapsing, inflammatory disorder classified
among the vasculitides [1, 2]. It has a worldwide distribution being more prevalent in the …