Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique
biophysical properties: a small headgroup; negative charge; and a phosphomonoester …

In eukaryotic cells, protein sorting is a highly regulated mechanism important for many
physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi …

The hippocampus is crucial for spatial memory formation, yet it does not store long-lasting
memories. By combining functional brain imaging and region-specific neuronal inactivation …

Mono‐ADP‐ribosylation is the enzymatic transfer of ADP‐ribose from NAD+ to acceptor
proteins. It is catalysed by cellular ADP‐ribosyltransferases and certain bacterial toxins …

The C-terminal binding protein (CtBP) family of proteins has been linked to multiple
biological processes through their association with numerous transcription factors. We …

The poly (ADP-ribose) polymerase tankyrase was originally described as a telomeric protein
whose catalytic activity was proposed to regulate telomere function. Subsequent studies …

Huntingtin is a protein of unknown function that contains a polyglutamine tract, which is
expanded in patients with Huntington's disease (HD). We investigated the localization and a …

The cytoskeleton plays important roles in plant cell shape determination by influencing the
patterns in which cell wall materials are deposited. Cortical microtubules are thought to …

During cell migration, integrins are redistributed from focal adhesions undergoing
disassembly at the cell's trailing edges to new focal adhesions assembling at leading edges …

Transcriptional repression is based on the selective actions of recruited corepressor
complexes, including those with enzymatic activities. One well-characterized …