Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

Subunit vaccines for Acinetobacter baumannii

N Yang, X Jin, C Zhu, F Gao, Z Weng, X Du… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen
in hospitals. A. baumannii infection has become a challenging problem in clinical practice …

Non-antibiotic prevention and treatment against Acinetobacter baumannii infection: Are vaccines and adjuvants effective strategies?

Y Hu, X Zhang, S Deng, C Yue, X Jia… - Frontiers in Microbiology, 2023 - frontiersin.org
Acinetobacter baumannii (A. baumannii) is a Gram-negative opportunistic pathogen widely
attached to the surface of medical instruments, making it one of the most common pathogens …

A novel mRNA multi-epitope vaccine of Acinetobacter baumannii based on multi-target protein design in immunoinformatic approach

Y Xu, F Zhu, Z Zhou, S Ma, P Zhang, C Tan, Y Luo… - BMC genomics, 2024 - Springer
Acinetobacter baumannii is a gram-negative bacillus prevalent in nature, capable of thriving
under various environmental conditions. As an opportunistic pathogen, it frequently causes …

Actinobacillus pleuropneumoniae, surface proteins and virulence: a review

MM Soto Perezchica, AL Guerrero Barrera… - Frontiers in Veterinary …, 2023 - frontiersin.org
Actinobacillus pleuropneumoniae (App) is a globally distributed Gram-negative bacterium
that produces porcine pleuropneumonia. This highly contagious disease produces high …

Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection

S Chaudhuri, I Rasooli, RH Oskouei… - Frontiers in …, 2022 - frontiersin.org
Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical
settings due to the emergence of antibiotic resistant strains and the lack of effective …

Combination of BauA and OmpA elicit immunoprotection against Acinetobacter baumannii in a murine sepsis model

M Tamehri, I Rasooli, M Pishgahi, A Jahangiri… - Microbial …, 2022 - Elsevier
Aims Acinetobacter baumannii causes severe nosocomial infections and is a difficult-to-treat
pathogen due to the development of multidrug-resistant (MDR) strains. Vaccines and …

A unique antigen against SARS-CoV-2, Acinetobacter baumannii, and Pseudomonas aeruginosa

MR Rahbar, SMH Mubarak, A Hessami, B Khalesi… - Scientific Reports, 2022 - nature.com
The recent outbreak of COVID-19 has increased hospital admissions, which could elevate
the risk of nosocomial infections, such as A. baumannii and P. aeruginosa infections …

In silico design of a novel hybrid epitope-based antigen harboring highly exposed immunogenic peptides of BamA, OmpA, and Omp34 against Acinetobacter …

A Hessami, Z Mogharari, F Rahim, B Khalesi… - International …, 2024 - Elsevier
Acinetobacter baumannii, is among the highest priority bacteria according to the WHO
categorization which necessitate the exploration of alternative strategies such as …

Immunization with recombinant DcaP-like protein and AbOmpA revealed protections against sepsis infection of multi-drug resistant Acinetobacter baumannii ST2Pas …

S Fereshteh, S Ajdary, A Sepehr, N Bolourchi… - Microbial …, 2023 - Elsevier
Backgrounds The prevalence of infections associated with multi-drug resistant (MDR)
Acinetobacter baumannii is increasing worldwide. Therefore, the introduction of effective …