Despite intense research efforts, our pharmaceutical repertoire against high-grade brain
tumours has not been able to increase patient survival for a decade and life expectancy …

MicroRNAs (miRNAs) are noncoding RNA molecules that regulate gene expression post-
transcriptionally and influence numerous biological processes. Aberrant miRNA expression …

Protein arginine methyltransferases (PRMTs) regulate diverse biological processes and are
increasingly being recognized for their potential as drug targets. Here we report the …

PRMT1 plays a vital role in breast tumorigenesis; however, the underlying molecular
mechanisms remain incompletely understood. Herein, we show that PRMT1 plays a critical …

MicroRNAs (miRNAs) play crucial roles in physiological functions and disease, but the
regulation of their nuclear biogenesis remains poorly understood. Here, BioID on Drosha …

Thyroid cancer is one of the most common malignant tumors, and the mortality rate
associated with thyroid cancer has been increasing annually. Curcumin has been reported …

Objective To understand the protective effect of NF-κB signaling pathway inhibitor
pyrrolidinedithiocarbamate (PDTC) on mice with chronic atrophic gastritis (CAG). Methods …

Accumulating evidences have revealed the dysregulated expressions and critical roles of
non-coding RNAs in various malignancies, including cervical cancer. Nevertheless, our …

RNA binding proteins (RBPs) bind RNAs through specific RNA-binding domains, generating
multi-molecular complexes known as ribonucleoproteins (RNPs). Various post-translational …

Protein methylation is receiving more and more attention due to its essential role in diverse
biological processes. Large-scale analysis of protein methylation requires the efficient …