Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …

All mammalian oocytes and eggs are surrounded by a relatively thick extracellular matrix
(ECM), the zona pellucida (ZP), that plays vital roles during oogenesis, fertilization, and …

The zona pellucida (ZP) is an extracellular matrix that surrounds all mammalian oocytes,
eggs, and early embryos and plays vital roles during oogenesis, fertilization, and …

Amyloid is an insoluble fibrous protein and its mis-aggregation can lead to some diseases,
such as Alzheimer's disease and Creutzfeldt–Jakob's disease. Therefore, the identification …

With the development of nanotechnology, functional amyloid materials are drawing
increasing attention, and numerous remarkable applications are emerging. Amyloids …

Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP
glycoprotein-1 (ZP1),-2 (ZP2),-3 (ZP3), and-4 (ZP4). Mutations in the genes encoding human …

Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

Fast, accurate identification and characterization of amyloid proteins at a large-scale is
essential for understating their role in therapeutic intervention strategies. As a matter of fact …

Soluble functional proteins may transform into insoluble amyloid fibrils that deposit in a
variety of tissues. Amyloid formation is a hallmark of age-related degenerative disorders …

Amyloids cause incurable diseases in humans and animals and regulate vital processes in
bacteria and eukaryotes. Amyloid fibrils have unique properties, such as amazing resistance …