The past five years have seen many scientific and biological discoveries made through the experimental design of genome-wide association studies (GWASs). These studies were …
Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining∼ 14% of the …
Most common breast cancer susceptibility variants have been identified through genome- wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease …
Genome-wide association studies (GWASs) have enabled the discovery of common genetic variation contributing to normal and pathological traits and clinical drug responses, but …
We present an approximate conditional and joint association analysis that can use summary- level statistics from a meta-analysis of genome-wide association studies (GWAS) and …
Psychiatric disorders are among the most intractable enigmas in medicine. In the past 5 years, there has been unprecedented progress on the genetics of many of these conditions …
… Depressive Disorder Working Group of the … - Molecular …, 2012 - pmc.ncbi.nlm.nih.gov
Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have met with limited success. We sought to increase statistical power to detect disease loci by …
AA Al Olama, Z Kote-Jarai, SI Berndt, DV Conti… - Nature …, 2014 - nature.com
Genome-wide association studies (GWAS) have identified 76 variants associated with prostate cancer risk predominantly in populations of European ancestry. To identify …
Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for∼ …