Advances in regenerative medicine for otolaryngology/head and neck surgery

MJ McPhail, JR Janus, DG Lott - Bmj, 2020 - bmj.com
Head and neck structures govern the vital functions of breathing and swallowing.
Additionally, these structures facilitate our sense of self through vocal communication …

Induction of fibrogenic phenotype in human mesenchymal stem cells by connective tissue growth factor in a hydrogel model of soft connective tissue

AB Zerdoum, EW Fowler, X Jia - ACS biomaterials science & …, 2019 - ACS Publications
Scar formation is the typical end point of wound healing in adult mammalian tissues. An
overactive or prolonged fibrogenic response following injury leads to excessive deposition …

Regulation of stem cell function in an engineered vocal fold-mimetic environment

AB Zerdoum, P Saberi, AJ Stuffer, DJ Kelly… - Regenerative …, 2020 - Springer
Human mesenchymal stem cells (hMSCs) have been proposed as therapeutic cells for the
treatment of vocal fold (VF) scarring. Although functional recovery was observed in animal …