The goal of a biomaterial is to support the bone tissue regeneration process at the defect site
and eventually degrade in situ and get replaced with the newly generated bone tissue …

Silk fibroin (SF) is a fibrous protein which is produced mainly by silkworms and spiders. Its
unique mechanical properties, tunable biodegradation rate and the ability to support the …

Our goal was to generate functionalized 3D-printed scaffolds for bone regeneration using
silk-hydroxyapatite bone cements and osteoinductive, proangiogenic and neurotrophic …

The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

Bone tissue plays multiple roles in our day-to-day functionality. The frequency of accidental
bone damage and disorder is increasing worldwide. Moreover, as the world population …

Biopolymers are materials synthesised or derived from natural sources, such as plants,
animals, microorganisms or any other living organism. The use of these polymers has grown …

The success of bone substitutes used to repair bone defects such as critical sized defects
depends on the architecture of the porous biomaterial. The architectural parameters and …

Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

Silk, a natural biopolymer, has been used clinically as suture material over thousands of
years and has received much impetus for a plethora of biomedical applications in the last …