Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The ability to adapt to altered availability of free water is a fundamental property of living
cells. The principles underlying osmoadaptation are well conserved. The yeast …

ASH1 mRNA localizes to the bud tip in Saccharomyces cerevisiae to establish asymmetry of
HO expression, important for mating type switching. To visualize real time localization of the …

Gene duplication is an important source of evolutionary novelty,. Most duplications are of
just a single gene, but Ohno proposed that whole-genome duplication (polyploidy) is an …

Nucleation of branched actin filaments by the Arp2/3 complex is a conserved process in
eukaryotic cells, yet the source of unbranched actin filaments has remained obscure. In …

Cdc42p is an essential GTPase that belongs to the Rho/Rac subfamily of Ras-like GTPases.
These proteins act as molecular switches by responding to exogenous and/or endogenous …

The Saccharomyces cerevisiae BNI1 gene product (Bni1p) is a member of the formin family
of proteins, which participate in cell polarization, cytokinesis, and vertebrate limb formation …

Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …

Gene activation in eukaryotes requires chromatin remodeling complexes like Swi/Snf and
histone acetylases like SAGA. How these factors are recruited to promoters is not yet …