Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

The immunosuppressive status of the tumor microenvironment (TME) remains poorly
defined due to a lack of understanding regarding the function of tumor-associated …

DAVID is a popular bioinformatics resource system including a web server and web service
for functional annotation and enrichment analyses of gene lists. It consists of a …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute
respiratory disease and multiorgan failure. Finding human host factors that are essential for …

Repeat expansion in C9ORF72 is the most common genetic cause of amyotrophic lateral
sclerosis (ALS) and frontotemporal dementia (FTD). Here we show that N 6 …

Selective targeting of aneuploid cells is an attractive strategy for cancer treatment. However,
it is unclear whether aneuploidy generates any clinically relevant vulnerabilities in cancer …

INTRODUCTION Cancer is a leading cause of death worldwide, and there is great need to
define the molecular mechanisms driving the development and progression of individual …

Cancer is a term that denotes a group of diseases caused by the abnormal growth of cells
that can spread in different parts of the body. According to the World Health Organization …

Most drugs entering clinical trials fail, often related to an incomplete understanding of the
mechanisms governing drug response. Machine learning techniques hold immense promise …

Metabolic coordination between neurons and astrocytes is critical for the health of the brain.
However, neuron-astrocyte coupling of lipid metabolism, particularly in response to neural …