Malaria is a devastating parasitic disease affecting half of the world's population. The rapid
emergence of resistance against new antimalarial drugs, including artemisinin‐based …

The ubiquitin/proteasome system serves as a regulated protein degradation pathway in
eukaryotes, and is involved in many cellular processes featuring high protein turnover rates …

Artemisinin (ART)-based combination therapies are the most efficacious treatment of
uncomplicated Plasmodium falciparum malaria. Alarmingly, P. falciparum strains have …

Quite aside from its immense importance as a human pathogen, studies in recent years
have brought to light the fact that the malaria parasite Plasmodium falciparum is an …

The proteasome plays a vital role throughout the life cycle as Plasmodium parasites quickly
adapt to a new host and undergo a series of morphologic changes during asexual …

Background Malaria is a major health and socio-economical problem in tropical and sub-
tropical areas of the world. Several methodologies have been used to assess parasite …

Malaria, caused by protozoan of genus Plasmodium, remains one of the highest mortality
infectious diseases. Malaria parasites have a complex life cycle, easily adapt to their host's …

Several protein quality control systems in bacteria and/or mitochondrial matrix from lower
eukaryotes are absent in higher eukaryotes. These are transfer-messenger RNA (tmRNA) …

The ATP-dependent ClpQY protease system in Plasmodium falciparum is a prokaryotic
machinery in the parasite. In the present study, we have identified the complete ClpQY …

The ATP‐dependent ClpQY system is a prokaryotic proteasome‐like multi‐subunit
machinery localized in the mitochondrion of malaria parasite. The ClpQY machinery consists …