Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning

JR Ferreira, GQ Teixeira, SG Santos… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine

FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

S Ji, M Xiong, H Chen, Y Liu, L Zhou, Y Hong… - … and Targeted Therapy, 2023 - nature.com
The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

[HTML][HTML] Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

S Halldorsson, E Lucumi, R Gómez-Sjöberg… - Biosensors and …, 2015 - Elsevier
Culture of cells using various microfluidic devices is becoming more common within
experimental cell biology. At the same time, a technological radiation of microfluidic cell …

Hypoxic hUCMSC-derived extracellular vesicles attenuate allergic airway inflammation and airway remodeling in chronic asthma mice

L Dong, Y Wang, T Zheng, Y Pu, Y Ma, X Qi… - Stem Cell Research & …, 2021 - Springer
Background As one of the main functional forms of mesenchymal stem cells (MSCs), MSC-
derived extracellular vesicles (MSC-EVs) have shown an alternative therapeutic option in …

[图书][B] Culture of animal cells: a manual of basic technique and specialized applications

RI Freshney - 2015 - books.google.com
Since the publication of the sixth edition of this benchmark text, numerous advances in the
field have been made–particularly in stem cells, 3D culture, scale-up, STR profiling, and …

Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo

J Beegle, K Lakatos, S Kalomoiris, H Stewart… - Stem …, 2015 - academic.oup.com
Mesenchymal stem cells/multipotent stromal cells (MSCs) are promising therapeutics for a
variety of conditions. However, after transplantation, cell retention remains extremely …

The role of hypoxia in bone marrow–derived mesenchymal stem cells: considerations for regenerative medicine approaches

R Das, H Jahr, GJVM van Osch… - Tissue Engineering Part B …, 2010 - liebertpub.com
Bone marrow–derived mesenchymal stem cells (MSCs) have demonstrated potential for
regenerative medicine strategies. Knowledge of the way these cells respond to their …

Laser printing of stem cells for biofabrication of scaffold-free autologous grafts

M Gruene, A Deiwick, L Koch, S Schlie… - … Engineering Part C …, 2011 - liebertpub.com
Stem cells are of widespread interest in regenerative medicine due to their capability of self-
renewal and differentiation, which is regulated by their three-dimensional microenvironment …

[HTML][HTML] Evolution of air breathing: oxygen homeostasis and the transitions from water to land and sky

CCW Hsia, A Schmitz, M Lambertz… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Life originated in anoxia, but many organisms came to depend upon oxygen for survival,
independently evolving diverse respiratory systems for acquiring oxygen from the …