Protein is one of the most important biological macromolecules in life, which plays a vital
role in cell growth, development, movement, heredity, reproduction and other life activities …

Viral vectors are poised to acquire a prominent position in modern medicine and
biotechnology owing to their role as delivery agents for gene therapies, oncolytic agents …

The administration of viral vectored vaccines remains one of the most effective ways to
respond to the ongoing novel coronavirus disease 2019 (COVID-19) pandemic. However …

The production of high-quality purified virus particles in high quantities for vaccine
preparation requires a scalable purification procedure in the downstream step. A purification …

Oncolytic viruses (OV) have emerged as a promising approach to mitigate the challenges of
treating solid cancers. However, the lack of established manufacturing and downstream …

This study investigated the potential of dual-ligand hydrophobic charge-induction
chromatography for the simultaneous recovery of two high-value components (bovine serum …

Newcastle disease virus (NDV), belonging to the species avian orthoavulavirus 1, genus
Orthoavulavirus, and family Paramyxoviridae, is responsible for Newcastle disease in …

The use of viral vectors for vaccine, gene therapy, and oncolytic virotherapy applications has
received increased attention in recent years. Large‐scale purification of viral vector‐based …

Background: Large-scale vaccine production requires downstream processing that focuses
on robustness, efficiency, and cost-effectiveness. Methods: To assess the robustness of the …

Vaccine production is growing significantly every day. Immunization has regained its critical
importance, particularly after the occurrence of the SARS-CoV-2 pandemic. When the entire …