Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants
belonging to licorice, including Glycyrrhiza uralensis, Mongolian glycyrrhiza, Glycyrrhiza …

Cholera is a diarrheal disease that remains an important global health problem with several
hundreds of thousands of reported cases each year. This disease is caused by intestinal …

Isoliquiritigenin (ISL), a natural flavonoid derived from the root of liquorice, has been
reported to possess anti-inflammatory and antioxidant activities. Previous studies have …

While infectious agents have typical host preferences, the noninvasive enteric bacterium
Vibrio cholerae is remarkable for its ability to survive in many environments, yet cause …

Cholera is a diarrheal disease causing significant morbidity and mortality worldwide. This
study aimed to establish an adult mouse model of Vibrio cholerae-induced diarrhea and to …

Objectives The oral rehydration solution is the most efficient method to treat cholera;
however, it does not interfere in the action mechanism of the main virulence factor produced …

Piperine is the principal alkaloid in black peppers (Piper nigrum L.), which is a commonly
included spice in anti-diarrheal formulations. Piperine has antispasmodic activities, but its …

Cystic fibrosis transmembrane conductance regulator (CFTR) is the principal apical route for
transepithelial fluid transport induced by enterotoxin. Inhibition of CFTR has been confirmed …

Epithelial Na+ transport participates in control of various body functions and conditions: eg,
homeostasis of body fluid content influencing blood pressure, control of amounts of fluids …

Secretory diarrhea is one of the most common causes of death world-wide especially in
children under 5 years old. Isoliquiritigenin (ISLQ), a plant-derived chalcone, has previously …