Diabetic kidney disease (DKD), one of the most severe complications of diabetes mellitus
(DM), has received considerable attention owing to its increasing prevalence and …

Diabetes mellitus (DM) causes damage to major organs, including the heart, liver, brain,
kidneys, eyes, and blood vessels, threatening the health of the individuals. Emerging …

AKT serine-threonine kinase (AKT) and its effectors are essential for maintaining cell
proliferation, apoptosis, autophagy, endoplasmic reticulum (ER) stress, mitochondrial …

Vascular complications are the main cause of diabetes mellitus-associated morbidity and
mortality. Oxidative stress and metabolic dysfunction underly injury to the vascular …

Increasing evidence suggests that insulin resistance in type 2 diabetes mellitus (T2DM) is
associated with mitochondrial dysfunction in skeletal muscle, while the underlying molecular …

Type 2 diabetes (T2D) is a metabolic disease with complex etiology and mechanisms. Long
non-coding ribonucleic acid (LncRNA) is a novel class of functional long RNA molecules …

Abstract Background IgA nephropathy (IgAN) is one of the most common primary glomerular
diseases worldwide, especially in young Asian adults. Long RNA H19 is associated with …

Abstract Calcium (Ca 2+) acts as a second messenger and constitutes a complex and large
information exchange system between the endoplasmic reticulum (ER) and mitochondria; …

Mitochondria are highly dynamic organelles that maintain their homeostasis through
mitochondrial dynamics. Mitochondrial fusion and fission are two important processes of …

The dysfunction of islet β-cells is one of the causes of diabetes, and lncRNA Gm10451 is
also a participant in the occurrence and the development of various diseases. This study …