Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Genetic analysis of Drosophila, mice and humans indicates that gene alleles, mutations and
transgenes that affect life span tend to do so differently depending on the sex of the …

The great majority of lifespan‐augmenting mutations were discovered in the nematode
Caenorhabditis elegans. In particular, genetic disruption of insulin‐like signaling extends …

Many lifespan-modulating genes are involved in either generation of oxidative substrates
and end-products, or their detoxification and removal. Among such metabolites, only …

The genetic variants underlying complex traits are often elusive even in powerful model
organisms such as Caenorhabditis elegans with controlled genetic backgrounds and …

Phenotypic plasticity and genotype–environment interactions (GEI) play an important role in
the evolution of life histories. Knowledge of the molecular genetic basis of plasticity and GEI …

Recombinant inbred lines (RILs) derived from Caenorhabditis elegans wild-type N2 and
CB4856 are increasingly being used for mapping genes underlying complex traits. To speed …

Представлен аналитический обзор достижений генетики старения и
продолжительности жизни. Обобщены эволюционные, клеточные и молекулярно …

Caenorhabditis elegans expresses a glutathione transferase (GST) belonging to the Pi
class, for which we propose the name CeGSTP2‐2. CeGSTP2‐2 (the product of the gst‐10 …

Empirical evidence is mounting to suggesting that genetic correlations between life-history
traits are environment specific. However, detailed knowledge about the loci underlying …