Targeting the sulfur-containing amino acid pathway in leukemia

X Chen, J Jin, R Chang, X Yang, N Li, X Zhu, L Ma, Y Li - Amino Acids, 2024 - Springer
Abstract sulfur-containing amino acids have been reported to patriciate in gene regulation,
DNA methylation, protein synthesis and other physiological or pathological processes. In …

Metabolic reprogramming in KRAS-mutant cancers: Proven targetable vulnerabilities and potential therapeutic strategies

R Wu, H Zhu, Q He, T Yuan, B Yang - Drug Discovery Today, 2024 - Elsevier
Abstract Kras (Ki-ras2 Kirsten rat sarcoma viral oncogene homolog), one of the most
frequently mutated oncogenes in the human genome, is considered 'untargetable'. Although …

Plasmonic array assisted mass spectrometry for preferential metabolite detection

X Li, W Chen, M Wu, W Yu, M Wang, M Niu… - Chemical Engineering …, 2024 - Elsevier
Metabolites, depicting physiological and pathophysiological state, underpin diverse disease-
associated phenomena. Metabolite detection offers insights for identifying disease …

A genetically encoded fluorescent protein sensor for mitochondrial membrane damage detection

Q Liu, D Wang, M Cui, M Li, XE Zhang - Biochemical and Biophysical …, 2024 - Elsevier
Mitochondria are essential cellular organelles; detecting mitochondrial damage is crucial in
cellular biology and toxicology. Compared with existing chemical probe detection methods …

Protective Effects of Tribulus terrestris Extract on Hepatotoxicity Induced by Cytarabine (Ara C) Chemotherapy in Male Rats

M Hassan - Kerbala Journal of Veterinary Medical Sciences, 2024 - kjvm.uokerbala.edu.iq
Hepatotoxicity is a common clinical manifestation associated with a wide range of anticancer
therapies. Because of the inherent toxicity of anticancer therapies, oncologists must maintain …