Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer's disease and dementia

M Nerattini, S Jett, C Andy, C Carlton… - Frontiers in aging …, 2023 - frontiersin.org
Introduction Despite a large preclinical literature demonstrating neuroprotective effects of
estrogen, use of menopausal hormone therapy (HT) for Alzheimer's disease (AD) risk …

Update on hormone therapy for the management of postmenopausal women

M Pan, X Pan, J Zhou, J Wang, Q Qi, L Wang - Bioscience trends, 2022 - jstage.jst.go.jp
Hormone therapy (HT) has been used in postmenopausal women for decades in clinical
practice. With further analysis and newer studies, the benefits and risks of HT have been …

Neuroactive steroids and Parkinson's disease: Review of human and animal studies

M Bourque, M Morissette, T Di Paolo - Neuroscience & Biobehavioral …, 2024 - Elsevier
The greater prevalence and incidence of Parkinson's disease (PD) in men suggest a
beneficial effect of sex hormones. Neuroactive steroids have neuroprotective activities thus …

Gender differences and quality of life in Parkinson's disease

P Crispino, M Gino, E Barbagelata… - International Journal of …, 2021 - mdpi.com
Parkinson's disease has been found to significantly affect health-related quality of life. The
gender differences of the health-related quality of life of subjects with Parkinson's disease …

[HTML][HTML] Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction

WQ Qiu, R Pan, Y Tang, XG Zhou, JM Wu, L Yu… - Biomedicine & …, 2020 - Elsevier
Emerging evidence indicates that the enhancement of microglial autophagy inhibits the
NLRP3 inflammasome mediated neuroinflammation in Alzheimer's disease (AD) …

[HTML][HTML] Cognitive health after menopause: does menopausal hormone therapy affect it?

P Stute, J Wienges, AS Koller, C Giese… - Best Practice & …, 2021 - Elsevier
Dementia is a pandemic chronic non-communicable disease. 10 in 100 women above age
65 will be diagnosed with dementia, primarily Alzheimer's disease (AD). Apart from age and …

Non-invasive brain stimulation and sex/polypeptide hormones in reciprocal interactions: a systematic review

J Veldema - Biomedicines, 2023 - mdpi.com
A better understanding of interindividual differences and the development of targeted
therapies is one of the major challenges of modern medicine. The sex of a person plays a …

A review on the application of the exposome paradigm to unveil the environmental determinants of age-related diseases

E Ding, Y Wang, J Liu, S Tang, X Shi - Human Genomics, 2022 - Springer
Age-related diseases account for almost half of all diseases among adults worldwide, and
their incidence is substantially affected by the exposome, which is the sum of all exogenous …

[HTML][HTML] Intersectionality in Alzheimer's disease: the role of female sex and Black American race in the development and prevalence of Alzheimer's disease

MB Misiura, B Butts, B Hammerschlag, C Munkombwe… - …, 2023 - Elsevier
It is well known that vascular factors and specific social determinants of health contribute to
dementia risk and that the prevalence of these risk factors differs according to race and sex …

Sex is a defining feature of neuroimaging phenotypes in major brain disorders

LE Salminen, MA Tubi, J Bright… - Human Brain …, 2022 - Wiley Online Library
Sex is a biological variable that contributes to individual variability in brain structure and
behavior. Neuroimaging studies of population‐based samples have identified normative …