Simple Summary Organ preservation strategies can be offered to patients with rectal cancer
that show a strong response to preoperative treatment in order to avoid major surgery …

Background To develop and compare delta-radiomics signatures from 2-(2D) and 3-
dimensional (3D) features that predict treatment outcomes following preoperative …

This study evaluated the prognostic impact of ACT in patients who achieved a pathological
complete response (pCR). Articles published from January 1990 to September 2018 were …

Purpose There are ongoing investigations to find promising biomarkers for predicting a
complete response (CR) after concurrent chemoradiation (CCRT) in rectal cancer. We …

Background The aim of this work is to combine radiological and pathological information of
tumor to develop a signature for pretreatment prediction of discrepancies of pathological …

Quantitative features extracted from biopsy digital pathology images can provide predictive
information for neoadjuvant chemoradiotherapy (nCRT) in local advanced rectal cancer …

Background & aims Obesity and low muscle mass are associated with worse outcomes of
colorectal cancer patients. We conducted a controlled trial to study the impact of a ketogenic …

Background Neoadjuvant therapy can lead to different tumor regression grades (TRG) in
rectal cancer after neoadjuvant therapy. The purposes of this study are to investigate the …

Simple Summary This study aims to evaluate the induction of immunogenic cell death (ICD)
for anticancer immunity by the novel topoisomerase I inhibitor lipotecan. These results show …

Background Accurately assessing the risk of recurrence in patients with locally advanced
rectal cancer (LARC) before treatment is important for the development of treatment …