The normal function of the hypothalamic-pituitary-adrenal (HPA) axis, and resultant
glucocorticoid (GC) secretion, is essential for human health. Disruption of GC regulation is …

Anterior pituitary folliculostellate (FS) cells, first described almost 50 years ago, have a wide
range of functions with respect to supporting and coordinating endocrine cell function, in …

Glucocorticoid (GC)-induced leucine zipper (GILZ) has been shown to mediate or mimic
several actions of GC. This study assessed the role of GILZ in self-resolving and GC-induced …

Translation is a basic cellular process and its capacity is adapted to cell function. In
particular, secretory cells achieve high protein synthesis levels without triggering the protein …

IGF-I is considered a primary inhibitor of GH secretion. Insulin may also play an important
role in regulating GH levels because insulin, like IGF-I, can suppress GH synthesis and …

Abstract Annexin A1 (ANXA1) expression is commonly reduced in premalignant lesions and
prostate cancer, but a causal relationship of ANAX1 loss with carcinogenesis has not been …

The anterior pituitary is exposed to ultradian, circadian and stress-induced rhythms of
circulating glucocorticoid hormones. Glucocorticoids feedback at the level of the pituitary …

Annexin A1 (ANXA1, formerly termed lipocortin 1 or macrocortin) is an important protein
mediator of the feedback actions of glucocorticoids within the hypothalamo-pituitary …

Abstract N-formylpeptide receptor 1 (FPR1) is a G protein-coupled receptor that mediates
pro-inflammatory chemotactic responses by phagocytic leukocytes to N-formylpeptides …

The adrenal gland influences a multitude of processes during stress response, but also
potently affects the immune system, glucose metabolism, electrolyte or water homeostasis …