Background This Commission addresses several priority areas for psychiatry over the next
decade, and into the 21st century. These represent challenges and opportunities for the …

Gut microbiome diversity has been strongly associated with mood-relating behaviours,
including major depressive disorder (MDD). This association stems from the recently …

This article addresses the integration problem in psychiatry: the explanatory problem of
integrating such heterogeneous factors as cause or contribute to the problems at hand …

Maslow's hierarchy of human motivation is an often-cited reference in articles on the practice
of psychotherapy. When approached to contribute these reflections I realised that I had …

Depression has been described as a process of behavioural withdrawal from overwhelming
aversive stressors, and which manifests itself in the diagnostic symptomatology for Major …

Depressive symptoms are reported by 20% of the population and are related to altered
functional integrity of large-scale brain networks. The link between moment-to-moment brain …

ABSTRACT The International Society of Psychiatric Genetics (ISPG) created a Residency
Education Committee with the purpose of identifying key genetic knowledge that should be …

Unlike other medical specialties, psychiatry has not been involved in the theoretical shift that
replaced the syndromal approach with the clinico-pathological method, which consists in …

The biological mechanisms underlying psychiatric diagnoses are not well defined. Clinical
diagnosis based on categorical systems exhibit high levels of heterogeneity and co …

Freud's central theories explained in the context of modern therapy. Often overlooked
because he is so easy to mock, ridicule, or just plain misunderstand, Freud introduced many …