[HTML][HTML] Lipoxin A4 (LXA4) as a Potential Drug for Diabetic Retinopathy

UN Das - Medicina, 2025 - mdpi.com
The purpose of this review is to propose that lipoxin A4 (LXA4), derived from arachidonic
acid (AA), a potent anti-inflammatory, cytoprotective, and wound healing agent, may be …

[HTML][HTML] Lipid Mediators in Glaucoma: Unraveling Their Diverse Roles and Untapped Therapeutic Potential

DJ Mathew, JM Sivak - Prostaglandins & Other Lipid Mediators, 2024 - Elsevier
Glaucoma is a complex neurodegenerative disease characterized by optic nerve damage
and visual field loss and remains a leading cause of irreversible blindness. Elevated …

Retinal cytoarchitecture is preserved in an organotypic perfused human and porcine eye model

D Chan, JW Zhang, GJ Won, JM Sivak - Acta Neuropathologica …, 2024 - Springer
Pathobiology of the intact human retina has been challenging to study due to its relative
inaccessibility and limited sample availability. Thus, there is a great need for new …

Suppression of the Host Humoral Immune Response by Clostridioides difficile Toxin B2

K Norman - 2024 - search.proquest.com
Recurrent Clostridioides difficile infection (CDI) results in significant morbidity and mortality.
The mechanisms behind these recurrences are unknown, but it is hypothesized that the …

Microglial P2y6 Receptor Knockdown Alleviates Neuroinflammation after Traumatic Brain Injury by Inhibiting the Cxcl10/Cxcr3 Axis

Z Huang, X Qian, M Li, R Gao, L Li - Available at SSRN 4917380 - papers.ssrn.com
Traumatic brain injury (TBI) is a severe neurological injury often accompanied by
neuroinflammatory responses. During the pathophysiological process of TBI, microglia are …