Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …

1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …

Therapeutic drug delivery across the blood-brain barrier (BBB) is not only inefficient, but also
nonspecific to brain stroma. These are major limitations in the effective treatment of brain …

Nonviral gene therapy holds great promise but has not delivered treatments for clinical
application to date. Lack of safe and efficient gene delivery vectors is the major hurdle …

Current therapies for most neurodegenerative disorders are only symptomatic in nature and
do not change the course of the disease. Gene therapy plays an important role in disease …

Poly (β-amino ester) s (PAEs) have emerged as a promising class of gene delivery vectors
with performances that can even be compared to viruses. However, all of the transfection …

Due to the significance of disulfide bonds within modern material and medicinal sciences,
much attention has been paid to the synthesis of disulfide-containing polymers. Within this …

Highly branched poly (β-amino esters)(HPAEs) are developed via a facile and controllable
“A2+ B3/B2” strategy successfully. As nonviral gene delivery vectors, the performance of …

Abstract The use of 2, 5‐diformylpyrrole in self‐assembly reactions with diamines and Zn
(II)/Cd (II) salts allowed the preparation of [2] catenane, trefoil knot, and Borromean rings …

Overexpression of the hepatocyte growth factor receptor/c-Met proto oncogene on the
surface of a variety of tumor cells gives an opportunity to specifically target cancerous …