• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Diabetic foot ulcers (DFU) are a major source of preventable morbidity in adults with
diabetes. Consequences of foot ulcers include decline in functional status, infection …

Importance Approximately 18.6 million people worldwide are affected by a diabetic foot ulcer
each year, including 1.6 million people in the United States. These ulcers precede 80% of …

Lower extremity peripheral artery disease (PAD) affects> 230 million adults worldwide and is
associated with increased risk of various adverse clinical outcomes (other cardiovascular …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Abstract The Wound Healing Foundation (WHF) recognised a need for an unbiased
consensus on the best treatment of chronic wounds. A panel of 13 experts were invited to a …

Neuropathy and ischaemia are two great pathologies of the diabetic foot which lead to the
characteristic features of foot ulceration (neuropathic and ischaemic) and Charcot …

Diabetic foot ulceration is a devastating complication of diabetes that is associated with
infection, amputation, and death, and is affecting increasing numbers of patients with …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …