Extracapsular spread in head and neck squamous cell carcinoma: a systematic review and meta-analysis

M Mermod, G Tolstonog, C Simon, Y Monnier - Oral oncology, 2016 - Elsevier
Extracapsular spread (ECS) is one of the most important prognostic factors in head and neck
squamous cell carcinoma (HNSCC). However, despite its major clinical relevance, there are …

Update on oral and oropharyngeal cancer staging-International perspectives

MG Kato, CH Baek, P Chaturvedi… - World journal of …, 2020 - mednexus.org
Squamous cell carcinoma of the oral cavity and oropharynx have been used synonymously
and interchangeably in the world literature in the context of head and neck cancers. As the …

Management of the neck in squamous cell carcinoma of the oral cavity and oropharynx: ASCO clinical practice guideline

SA Koyfman, N Ismaila, D Crook, A D'Cruz… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The aim of the current work is to provide evidence-based recommendations to
practicing physicians and others on the management of the neck in patients with squamous …

Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma

VB Wreesmann, N Katabi, FL Palmer… - Head & …, 2016 - Wiley Online Library
Background An objective definition of clinically relevant extracapsular nodal spread (ECS) in
head and neck squamous cell carcinoma (SCC) is unavailable. Methods Pathologic review …

Extracapsular spread and adjuvant therapy in human papillomavirus‐related, p16‐positive oropharyngeal carcinoma

P Sinha, JS Lewis Jr, JF Piccirillo, D Kallogjeri… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Extracapsular spread (ECS) is commonly used to justify adjuvant
chemotherapy in patients with head and neck cancer. The role of ECS as a prognosticator …

Extracapsular spread in head and neck carcinoma: impact of site and human papillomavirus status

JH Maxwell, RL Ferris, W Gooding, D Cunningham… - Cancer, 2013 - Wiley Online Library
BACKGROUND Extracapsular spread (ECS) in cervical lymph node metastases from head
and neck squamous cell carcinoma (SCC) is regarded as an adverse prognostic factor and …

The prognostic value of extranodal extension in human papillomavirus‐associated oropharyngeal squamous cell carcinoma

YI An, HS Park, JR Kelly, JM Stahl, WG Yarbrough… - Cancer, 2017 - Wiley Online Library
BACKGROUND Extranodal (or extracapsular) extension (ENE) is an adverse prognostic
factor in patients with head and neck cancers who undergo primary surgery. However, the …

Detectable postoperative circulating tumor human papillomavirus DNA and association with recurrence in patients with HPV-associated oropharyngeal squamous cell …

DM Routman, S Kumar, BS Chera, KR Jethwa… - International Journal of …, 2022 - Elsevier
Purpose The purpose of our study is to determine the rate of detectability of ctHPVDNA after
surgery but before adjuvant therapy in patients with human papillomavirus (HPV)-associated …

High metastatic node number, not extracapsular spread or N-classification is a node-related prognosticator in transorally-resected, neck-dissected p16-positive …

P Sinha, D Kallogjeri, H Gay, WL Thorstad, JS Lewis Jr… - Oral oncology, 2015 - Elsevier
Background Due to unique biology and prognosis, precise identification of predictive
parameters is critical for p16+ oropharyngeal squamous cell carcinoma (OPSCC). Prior …

Prognostic factors and survival unique to surgically treated p16+ oropharyngeal cancer

BH Haughey, P Sinha - The Laryngoscope, 2012 - Wiley Online Library
Abstract Objectives/Hypothesis: Current head and neck epidemiology demonstrates a
steadily increasing incidence of p16+ human papillomavirus‐related oropharynx squamous …