Micronuclei (MN) are extra-nuclear bodies that contain damaged chromosome fragments
and/or whole chromosomes that were not incorporated into the nucleus after cell division …

Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

DNA methylation is an epigenetic mark that has suspected regulatory roles in a broad range
of biological processes and diseases. The technology is now available for studying DNA …

The pentose phosphate pathway (PPP) is a fundamental component of cellular metabolism.
The PPP is important to maintain carbon homoeostasis, to provide precursors for nucleotide …

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …

DNA methylation plays a key role in regulating eukaryotic gene expression. Although
mitotically heritable and stable over time, patterns of DNA methylation frequently change in …

The biological significance of interactions of nuclear proteins with DNA in the context of
gene expression, cell differentiation, or disease has immensely been enhanced by the …

DNA methylation plays an important role in gene regulation in animals. However, the
evolution and function of DNA methylation has only recently emerged as the subject of …

Combinational pharmacotherapy with the synergistic/additive effect is a powerful treatment
strategy for complex diseases such as malignancies. Identifying synergistic combinations …

An improved method for detecting coronary heart disease (CHD) could have substantial
clinical impact. Building on the idea that systemic effects of CHD risk factors are a …