In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

Imaging has an essential role in the planning and delivery of radiotherapy. Recent advances
in imaging have led to the development of advanced radiotherapy techniques—including …

Simple Summary Oxygen-guided radiotherapy is a new modality for cancer irradiation.
Spatially Fractionated Radiation Therapy allows the treatment of hypoxic tumor areas with …

Radiomics is a recent area of research in precision medicine and is based on the extraction
of a large variety of features from medical images. In the field of radiation oncology …

LET-painting was suggested as a method to overcome tumour hypoxia. In vitro experiments
have demonstrated a well-established relationship between the oxygen enhancement ratio …

Hypoxia in solid tumors is one of the seminal mechanisms for developing aggressive trait
and treatment resistance in solid tumors. This evolutionarily conserved biological …

Hypoxia is a common feature of solid tumors that contributes to angiogenesis, invasiveness,
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …

Severe hypoxia [oxygen partial pressure (pO2) below 5–10 mmHg] is more frequent in
glioblastoma multiforme (GBM) compared to lower-grade gliomas. Seminal studies in the …

Hypoxia results from an imbalance between oxygen supply and consumption. It is a
common phenomenon in solid malignant tumors such as head and neck cancer. As hypoxic …

Awareness increases that the tumor biology influences treatment outcome and prognosis in
cancer. Tumor hypoxia is thought to decrease sensitivity to radiotherapy and some forms of …