Therapeutic drug monitoring of tyrosine kinase inhibitors using dried blood microsamples

N Verougstraete, V Stove, AG Verstraete… - Frontiers in …, 2022 - frontiersin.org
Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKIs) is not yet performed
routinely in the standard care of oncology patients, although it offers a high potential to …

Dried blood microsampling-assisted therapeutic drug monitoring of immunosuppressants: an overview

S Deprez, CP Stove - Journal of Chromatography A, 2023 - Elsevier
In the field of solid organ transplantation, chemotherapy and autoimmune disorders,
treatment with immunosuppressant drugs requires intensive follow-up of the blood …

Application of non-contact hematocrit prediction technologies to overcome hematocrit effects on immunosuppressant quantification from dried blood spots

S Deprez, L Heughebaert, L Boffel, CP Stove - Talanta, 2023 - Elsevier
Fully automated dried blood spot (DBS) analysis for therapeutic drug monitoring (TDM) of
the immunosuppressants tacrolimus, sirolimus, everolimus and cyclosporin A suffers from a …

Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns

A Derobertmasure, LS Toh, C Verstuyft… - British Journal of …, 2024 - Wiley Online Library
Aims Therapeutic drug monitoring for astronauts faces limitations in conventional blood
sampling and sample management onboard the international space station. Here, we …

Enhancing drug development and clinical studies with patient‐centric sampling using microsampling techniques: Opportunities, challenges, and insights into liquid …

Z Chen, CC Goudarzi, TW Sikorski… - Journal of Mass …, 2024 - Wiley Online Library
Microsampling has revolutionized pharmaceutical drug development and clinical research
by reducing sample volume requirements, allowing sample collection at home or …

MSACL 2023 Abstract (s) for Liesl Heughebaert

L Heughebaert - msacl.org
Objectives: Recently, a UV-Vis-based Hct prediction module has been incorporated into the
automated CAMAG® DBS-MS 500 HCT system. However, besides a proof-of-principle, no …

[HTML][HTML] MSACL 2023 Abstract (s) for Tox/TDM/Endocrine

J Halifax - msacl.org
Objectives: To demonstrate the effectiveness of utilizing a clinically validated LC-QTOF-MS
comprehensive drug screen method to analyze street drug products to evaluate, confirm …

[HTML][HTML] MSACL 2024 Abstract

B Vadhwana - msacl.org
Background Gastro-esophageal reflux disease (GERD) is a common chronic gastrointestinal
disease with an increasing prevalence worldwide affecting up to 30% of the population in …