Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Hepatitis B virus (HBV), an enveloped partially double-stranded DNA virus, is a widespread
human pathogen responsible for more than 250 million chronic infections worldwide …

Ketamine produces rapid antidepressant action in patients with major depression or
treatment-resistant depression. Studies have identified brain-derived neurotrophic factor …

Endocytosis is a process essential to the health and well-being of cell. It is required for the
internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of …

Pancreatic cancer has the lowest 5 year survival rate among all cancers. Several
extracellular factors are involved in the development and metastasis of pancreatic cancer to …

Endocytosis is a fundamental mechanism by which cells perform housekeeping functions. It
occurs via a variety of mechanisms and involves many regulatory proteins. The GTPase …

Dynamin 2 mechanoenzyme is a key regulator of membrane remodeling and gain-of-
function mutations in its gene cause centronuclear myopathies. Here, we investigate the …

Cardiovascular disease (CVD) is the leading cause of mortality worldwide claiming almost
17. 9 million deaths annually. A primary cause is atherosclerosis within the coronary …

Breast cancer cells abnormally express vasopressin (AVP) and its receptors. The effect of
AVP is largely orchestrated through its downstream signaling and by receptor-mediated …