Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

In the early stage of osteoarthritis (OA), cartilage degradation in the surface region leads to
superficial cartilage defect. However, enhancing the regeneration of cartilage defect remains …

Diabetic wounds are characterized by drug‐resistant bacterial infections, biofilm formation,
impaired angiogenesis and perfusion, and oxidative damage to the microenvironment …

As chondrocytes from osteoarthritic cartilage usually exhibit aging and senescent
characteristics, targeting aging chondrocytes could be a potential therapeutic strategy. In this …

Osteoarthritis is a degenerative disorder that can severely affect joints, and new treatment
strategies are urgently needed. Administration of mesenchymal stem cell (MSC)‐derived …

The goal of a biomaterial is to support the bone tissue regeneration process at the defect site
and eventually degrade in situ and get replaced with the newly generated bone tissue …