Amnion-derived hydrogels as a versatile platform for regenerative therapy: from lab to market

G Kafili, H Niknejad, E Tamjid, A Simchi - Frontiers in Bioengineering …, 2024 - frontiersin.org
In recent years, the amnion (AM) has emerged as a versatile tool for stimulating tissue
regeneration and has been of immense interest for clinical applications. AM is an abundant …

Succinate/NLRP3 inflammasome induces synovial fibroblast activation: therapeutical effects of clematichinenoside AR on arthritis

Y Li, JY Zheng, JQ Liu, J Yang, Y Liu, C Wang… - Frontiers in …, 2016 - frontiersin.org
Clematichinenoside AR (C-AR) is a triterpene saponin isolated from the root of Clematis
manshurica Rupr., which is a herbal medicine used in traditional Chinese medicine for the …

[HTML][HTML] Moringa oleifera ethanolic extract attenuates tilmicosin-induced renal damage in male rats via suppression of oxidative stress, inflammatory injury, and …

SM Abou-Zeid, AI Ahmed, A Awad… - Biomedicine & …, 2021 - Elsevier
Tilmicosin (Til) is a popular macrolide antibiotic, widely used in veterinary practice. The
present study was designed to address the efficacy of Moringa oleifera ethanolic extract …

Acute toxic responses of embryo-larval zebrafish to zinc pyrithione (ZPT) reveal embryological and developmental toxicity

Y Zhao, Y Liu, J Sun, H Sha, Y Yang, Q Ye, Q Yang… - Chemosphere, 2018 - Elsevier
Zinc pyrithione (ZPT) is widely used in industrial and human daily life, due to its broad
antimicrobial spectrum activity. Persistent accumulation of ZTP in the aquatic environment …

[HTML][HTML] Bile duct ligature in young rats: A revisited animal model for biliary atresia

M Garrido, C Escobar, C Zamora, C Rejas… - European journal of …, 2017 - ncbi.nlm.nih.gov
Biliary atresia leads to cirrhosis in the vast majority of patients and constitutes the first cause
of paediatric liver transplantation. Animal models allow us to understand the molecular basis …

Curcumin inhibits hepatic stellate cell activation via suppression of succinate-associated HIF-1α induction

L She, D Xu, Z Wang, Y Zhang, Q Wei, J Aa… - Molecular and cellular …, 2018 - Elsevier
Purpose Aberrant succinate accumulation emerges as a unifying mechanism for
inflammation and oxidative stress. This study aims to investigate whether curcumin …

MicroRNA134 Mediated Upregulation of JNK and Downregulation of NFkB Signalings Are Critically Involved in Dieckol Induced Antihepatic Fibrosis

SY Lee, J Lee, HJ Lee, B Kim, J Lew… - Journal of agricultural …, 2016 - ACS Publications
Though Dieckol, a phlorotannin of Ecklonia cava, was known to have antioxidant,
anticancer, antidiabetic, and anti-inflammatory effects, the underlying antifibrotic mechanism …

Differential susceptibility of kidneys and livers to proliferative processes and transcriptional level of the genes encoding desmin, vimentin, connexin 43, and nestin in …

A Awad, SR Khalil, MR Farag, MA Nassan - … and Environmental Safety, 2018 - Elsevier
In this study, we aimed to assess the differential toxic impact, induced by furan exposure, on
the liver and kidney tissues by estimating reactive oxygen species (ROS) level, total …

Sildenafil protects against bile duct ligation induced hepatic fibrosis in rats: Potential role for silent information regulator 1 (SIRT1)

DM Abd El Motteleb, IAAEH Ibrahim… - Toxicology and applied …, 2017 - Elsevier
Hepatic fibrosis is a potential health problem that may end with life-threatening cirrhosis and
primary liver cancer. Recent studies point out to the protective effects of silent information …

Intermediate filament protein expression pattern and inflammatory response changes in kidneys of rats receiving doxorubicin chemotherapy and quercetin

SR Khalil, AT Mohammed, AH Abd El-fattah… - Toxicology Letters, 2018 - Elsevier
The aim of this study was to explore the potential effects of quercetin (QUR) on doxorubicin
(DOX)-induced nephrotoxicity. Fifty male rats were assigned to five groups (10 rats each): a …