Natural products have historically been of crucial importance in the identification and
development of antibacterial agents. Interest in these systems has waned in recent years …

Natural products have historically been, and continue to be, an invaluable source for the
discovery of various therapeutic agents. Oridonin, a natural diterpenoid widely applied in …

Oridonin, a diterpenoid natural product commonly used in East Asian herbal medicine, is
garnering increased attention in the biomedical community due to its extensive biological …

As medicine advances, cancer is still among one of the major health problems, posing
significant threats to human health. New anticancer agents features with novel scaffolds …

The cytotoxicity of the natural ent-kaurene diterpenoid, oridonin, has been extensively
studied. However, the application of oridonin for cancer therapy was hampered primarily by …

Pyrazine is a six-membered heterocyclic ring containing nitrogen, and many of its
derivatives are biologically active compounds. References have been downloaded through …

Oridonin (ORI), an ent-kaurene tetracyclic diterpenoid compound, is isolated from Chinese
herb Rabdosia rubescens with various biological and pharmacological activities including …

Oridonin belongs to ent-kaurane tetracyclic diterpenoid and was first isolated from Isodon
species. It exhibits inhibitory activities against a variety of tumor cells, and pharmacological …

Aging is a major risk factor for chronic diseases and disability in humans. Nowadays, no
effective anti-aging treatment is available clinically. In this study, oridonin was selected …

Covering: January to December 2013. Previous review, Nat. Prod. Rep., 2013, 30, 1346–
1356 This review covers the isolation and chemistry of diterpenoids from terrestrial as …