'Homeotic'transformations are developmental anomalies in which one part of the body
develops iiJ the likeness of another. Many cases of homeosis were described and the …

In Drosophila, homeotic genes of the Antennapedia (ANTC) and Bithorax (BX-C) complexes
specify the distinctions between different segments of the body. Each of these genes …

This paper reports the cloning of the fourth major murine homeogene complex, HOX‐5. The
partial characterization of this gene cluster revealed the presence of two novel genes (Hox …

In situ hybridization analysis of mouse embryos shows the seven members of the Hex-2
complex to be differentially expressed in the central and peripheral nervous system and in …

Mice homozygous for a targeted mutation of the Hoxa-2 (Hox 1.11) gene are born with cleft
palates and die within 24 hr of birth. Analysis of stained skeletons revealed that homozygous …

Various strategies have been used to isolate genes that participate in the regulation of
mouse development. Gene families that have been identified on the basis of their homology …

The cloning, characterization and developmental expression patterns of two novel murine
Hox genes, Hox‐4.6 and Hox‐4.7, are reported. Structural data allow us to classify the four …

The Hox-T. 6 gene disrupted in embryonic stem cells by homologous recombination was
introduced into the mouse germline. Heterorygous mice were normal, but homozygous mice …

Gene targeting in mouse embryo-derived stem cells has been used to generate mice with a
disruption in the homeobox gene Hox–1.6. Mice heterozygous at the Hox-# 150; 1.6 locus …

We describe the cloning from a rat islet somatostatin‐producing cell line of a 1.4 kb cDNA
encoding a new homeoprotein, IDX‐1 (islet/duodenum homeobox‐1), with close sequence …