Antibiotic resistance poses a tremendous threat to human health. To overcome this problem,
it is essential to know the mechanism of antibiotic resistance in antibiotic-producing and …

The construction of aromatic rings has become a key objective for organic chemists. While
several strategies have been developed for the functionalization of pre-formed aromatic …

A new strategy for the catalytic synthesis of substituted 1 H-indenes via metalloradical
activation of o-cinnamyl N-tosyl hydrazones is presented, taking advantage of the intrinsic …

Arylallyl alcohols are commonly found in natural products and drug molecules. The
traditional syntheses primarily rely on two-component reactions using presynthesized …

A new benzyne transformation is described that affords versatile biaryl structures without
recourse to transition‐metal catalysis or stoichiometric amounts of organometallic building …

Isobenzofulvene species are versatile synthons in organic chemistry, which have been
employed in diverse challenging higher‐order cycloaddition reactions. Here, the first …

A cascade reaction between 2‐styrylbenzaldehydes and indoles has been developed for
the synthesis of 1H‐indenes. An iodine‐catalyzed nucleophilic addition of indoles to an …

Herein, we report the rhodium-catalyzed domino arylation/cyclization reaction of unactivated
internal alkynes to afford the optically active indenols in excellent yields (up to 92%) and …

For the first time a general overview of approaches to the synthesis of natural product
analogues is presented. This reflects a process of evolution of natural product synthesis …

Two novel enediyne-derived natural products, amycolamycins A and B (1 and 2), were
characterized from a locust-associated actinomycete Amycolatopsis sp. HCa4 …