Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a
highly conserved, fundamental posttranslational modification (PTM). PARP catalytic …

An increase in the incidence of inflammatory arthritis after COVID-19 has been reported.
Since many diseases exhibit population-specific causal effect sizes, we aimed to evaluate …

Resistance mechanisms to immune checkpoint blockade therapy (ICBT) limit its response
duration and magnitude. Paradoxically, Interferon γ (IFNγ), a key cytokine for cellular …

Poly (ADP‐ribose) polymerases (PARP s) regulate the function of target proteins by
modifying them with ADP‐ribose, a large and unique post‐translational modification …

The literature review presented here details recent research involving members of the poly
(ADP-ribose) polymerase (PARP) family of proteins. Among the 17 recognized members of …

Poly-adenosine diphosphate-ribose polymerase (PARP) implements posttranslational mono-
or poly-ADP-ribosylation modification of target proteins. Among the known 18 members in …

Abstract Poly (ADP-ribose) polymerases (PARPs) are ADP-ribosylating enzymes and play
important roles in a variety of cellular processes. Most small-molecule PARP inhibitors …

ADP‐ribosylation is the addition of one or more (up to some hundreds) ADP‐ribose moieties
to acceptor proteins. This evolutionary ancient post‐translational modification (PTM) is …

Macroautophagy is regarded as a nonspecific bulk degradation process of cytoplasmic
material within the lysosome. However, the process has mainly been studied by nonspecific …

Poly (ADP-ribose) polymerase, member 14 (PARP14, alternatively named ARTD8, BAL2,
and COAST6) is an intracellular mono (ADP-ribosyl) transferase. PARP14 transfers a …