Discovery of shared genomic loci using the conditional false discovery rate approach
In recent years, genome-wide association study (GWAS) sample sizes have become larger,
the statistical power has improved and thousands of trait-associated variants have been …
the statistical power has improved and thousands of trait-associated variants have been …
Novel risk markers and risk assessments for cardiovascular disease
The use of risk markers has transformed cardiovascular medicine, exemplified by the routine
assessment of troponin, for both diagnosis and assessment of prognosis in patients with …
assessment of troponin, for both diagnosis and assessment of prognosis in patients with …
Shared genetic loci between depression and cardiometabolic traits
Epidemiological and clinical studies have found associations between depression and
cardiovascular disease risk factors, and coronary artery disease patients with depression …
cardiovascular disease risk factors, and coronary artery disease patients with depression …
Etiologic puzzle of coronary artery disease: how important is genetic component?
In the modern era, coronary artery disease (CAD) has become the most common form of
heart disease and, due to the severity of its clinical manifestations and its acute …
heart disease and, due to the severity of its clinical manifestations and its acute …
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
The most recent genome-wide association studies (GWAS) of schizophrenia (SCZ) identified
hundreds of risk variants potentially implicated in the disease. Further, novel statistical …
hundreds of risk variants potentially implicated in the disease. Further, novel statistical …
[HTML][HTML] Rationale and design of a genetic study on cardiometabolic risk factors: protocol for the Tehran Cardiometabolic Genetic Study (TCGS)
MS Daneshpour, MS Fallah… - JMIR research …, 2017 - researchprotocols.org
Background: Cardiometabolic risk factors comprise cardiovascular diseases and/or
diabetes, and need to be evaluated in different fields. Objective: The primary aim of the …
diabetes, and need to be evaluated in different fields. Objective: The primary aim of the …
Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans–Evidence from untargeted mRNA and miRNA studies
Cardiovascular and metabolic disorders present major causes of mortality in the ageing
population. Polyphenols present in human diets possess cardiometabolic protective …
population. Polyphenols present in human diets possess cardiometabolic protective …
Role of the adaptive immune system in atherosclerosis
K Ley - Biochemical Society Transactions, 2020 - portlandpress.com
Atherosclerosis, the pathology underlying heart attacks, strokes and peripheral artery
disease, is a chronic inflammatory disease of the artery wall initiated by elevated low-density …
disease, is a chronic inflammatory disease of the artery wall initiated by elevated low-density …
Genetic relations between type 1 diabetes, coronary artery disease and leukocyte counts
Aims/hypothesis Type 1 diabetes is associated with excess coronary artery disease (CAD)
risk even when known cardiovascular risk factors are accounted for. Genetic perturbation of …
risk even when known cardiovascular risk factors are accounted for. Genetic perturbation of …
Utilizing nutritional genomics to tailor diets for the prevention of cardiovascular disease: a guide for upcoming studies and implementations
D Corella, O Coltell, G Mattingley, JV Sorli… - Expert review of …, 2017 - Taylor & Francis
Introduction: Personalized diets based on an individual's genome to optimize the success of
dietary intervention and reduce genetic cardiovascular disease (CVD) risk, is one of the …
dietary intervention and reduce genetic cardiovascular disease (CVD) risk, is one of the …