Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

Complement system part II: role in immunity

NS Merle, R Noe, L Halbwachs-Mecarelli… - Frontiers in …, 2015 - frontiersin.org
The complement system has been considered for a long time as a simple lytic cascade,
aimed to kill bacteria infecting the host organism. Nowadays, this vision has changed and it …

Complement component C3–The “Swiss Army Knife” of innate immunity and host defense

D Ricklin, ES Reis, DC Mastellos, P Gros… - Immunological …, 2016 - Wiley Online Library
As a preformed defense system, complement faces a delicate challenge in providing an
immediate, forceful response to pathogens even at first encounter, while sparing host cells in …

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

TJ Foster, JA Geoghegan, VK Ganesh… - Nature reviews …, 2014 - nature.com
Staphylococcus aureus is an important opportunistic pathogen and persistently colonizes
about 20% of the human population. Its surface is' decorated'with proteins that are covalently …

The staphylococcal biofilm: adhesins, regulation, and host response

AE Paharik, AR Horswill - Virulence mechanisms of bacterial …, 2016 - Wiley Online Library
The Staphylococcus genus includes a diverse group of commensals that colonize mammals
on the skin or mucous membranes. Some of the best‐known members of this genus, such as …

Virulence factors and clonal diversity of Staphylococcus aureus in colonization and wound infection with emphasis on diabetic foot infection

K Shettigar, TS Murali - European Journal of Clinical Microbiology & …, 2020 - Springer
Foot ulcer is a common complication in diabetic subjects and infection of these wounds
contributes to increased rates of morbidity and mortality. Diabetic foot infections are caused …

Neutrophils and immunity: from bactericidal action to being conquered

TS Teng, A Ji, XY Ji, YZ Li - Journal of immunology research, 2017 - Wiley Online Library
The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …

Neutrophils Versus Staphylococcus aureus: A Biological Tug of War

AN Spaan, BGJ Surewaard, R Nijland… - Annual review of …, 2013 - annualreviews.org
The pathogen Staphylococcus aureus is well adapted to its human host. Neutrophil-
mediated killing is a crucial defense system against S. aureus; however, the pathogen has …

Staphylococcus aureus

TJ Foster - Molecular medical microbiology, 2002 - Elsevier
Publisher Summary The natural habitat of Staphylococcus aureus in humans is the skin and
nasopharynx. It can cause a wide variety of infections involving skin and soft tissues …

Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus

RS Flannagan, B Heit, DE Heinrichs - Pathogens, 2015 - mdpi.com
Habitually professional phagocytes, including macrophages, eradicate microbial invaders
from the human body without overt signs of infection. Despite this, there exist select bacteria …