Photodynamic therapy (PDT) is a potentially immunogenic and FDA‐approved antitumor
treatment modality that utilizes the spatiotemporal combination of a photosensitizer, light and …

Bladder-related diseases are among the most common and costly to the healthcare system,
and therefore require new approaches to treatment. Organoids and spheroids are 3D …

An evaluation of the leishmanicidal activity in vitro and in vivo of hypericin, an expanded-
spectrum photosensitizer found in Hypericum perforatum, is presented. Hypericin was …

Hypericin (Hyp) is used as a powerful natural photosensitizer in photodynamic therapy
(PDT). After selective accumulation in tumor tissue, vessels and matrix, and activated by …

Background Fusarium has been considered an opportunistic pathogen, causing several
infections in humans, including onychomycosis. In addition, a high resistance to …

Aspects related to the response of cells to photodynamic therapy (PDT) have been well
studied in cell cultures, which often grow in monolayers. In this work, we propose a …

Hypericin is a bright red fluorescent compound that can be used in urological medicine as a
photodiagnostic to detect non-muscle-invasive bladder cancer lesions. To this end a bladder …

Hypericin is a photosensitizer expressing high affinity for cancerous cells in vivo. Diagnosis
of cancer based on hypericin fluorescence imaging has been successfully assessed in …

Polyvinylpyrrolidone (PVP)-hypericin is a potent photosensitizer that is used in the urological
clinic to photodiagnose with high-sensitivity nonmuscle invasive bladder cancer (NMIBC) …

Clinical outcome of patients suffering from head neck squamous cell carcinomas is still poor
due to recurrent disease and surgical limitations. There is still a demand for multimodality …