Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Targeting of PARP enzymes has emerged as an effective therapeutic strategy to selectively
target cancer cells with deficiencies in homologous recombination signaling. Currently used …

Recent insights into histopathological and molecular subgroups of glioma have
revolutionized the field of neuro-oncology by refining diagnostic categories. An emblematic …

Abstract Poly (ADP-ribose) polymerase-1 (PARP-1) is a key enzyme in the DNA repair
process, and the overexpression of PARP-1 in several tumours makes this enzyme a …

Background Visual inspection and biopsy is the current standard of care for oral cancer
diagnosis, but is subject to misinterpretation and consequently to misdiagnosis. Topically …

Given the clinical potential of poly (ADP-ribose) polymerases (PARP) imaging for the
detection and stratification of various cancers, the development of novel PARP imaging …

DNA damage response (DDR) comprising DNA repair and cell-cycle checkpoint pathways,
is considered as a protective process that maintains the integrity of the genome. However …

Poly (adenosine diphosphate ribose) polymerase (PARP) has emerged as an effective
therapeutic strategy against cancer that targets the DNA damage repair enzyme. PARP …

Advanced ovarian cancer currently has few therapeutic options. Poly (ADP-ribose)
polymerase (PARP) inhibitors bind to nuclear PARP and trap the protein-inhibitor complex to …

Simple Summary In the realm of neurology, advanced imaging tools play a crucial role as
critical endpoints in clinical trials. While magnetic resonance imaging (MRI) serves as a …