Proinflammatory environment and role of TNF-α in endometrial function of obese women having polycystic ovarian syndrome

L Oróstica, I Astorga, F Plaza-Parrochia… - International journal of …, 2016 - nature.com
Methods: Serum and endometrial tissues were obtained from four study groups: normal-
weight, normal-weight-PCOS, obese and obese-PCOS (hyperandrogenemia …

Pro-inflammatory markers negatively regulate IRS1 in endometrial cells and endometrium from women with obesity and PCOS

L Oróstica, C Poblete, C Romero, M Vega - Reproductive Sciences, 2020 - Springer
A pro-inflammatory environment is characteristic of obesity and polycystic ovary syndrome
(PCOS). This environment through cytokines secretion negatively affects insulin action …

Metformin treatment regulates the expression of molecules involved in adiponectin and insulin signaling pathways in endometria from women with obesity-associated …

ML Oróstica, I Astorga, F Plaza-Parrochia… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is an endocrine/metabolic disorder associated with
insulin resistance (IR) and obesity. Endometria from women with PCOS present failures in …

Endometria from obese PCOS women with hyperinsulinemia exhibit altered adiponectin signaling

V García, L Oróstica, C Poblete, C Rosas… - Hormone and …, 2015 - thieme-connect.com
Hyperandrogenemia, hyperinsulinemia, and obesity affect 60–70% of patients with
Polycystic Ovarian Syndrome (PCOS), who exhibit an altered endometrial insulin signaling …

Metformin treatment regulates the expression of molecules involved in adiponectin and insulin signaling pathways in endometria from women with obesity-associated …

ML Oróstica Arévalo, I Astorga Leiva, F Plaza Parrochia… - 2022 - repositorio.uchile.cl
Polycystic ovary syndrome (PCOS) is an endocrine/metabolic disorder associated with
insulin resistance (IR) and obesity. Endometria from women with PCOS present failures in …

Proinflammatory environment and role of TNF-α in endometrial function of obese women having polycystic ovarian syndrome

ML Oróstica Arévalo, I Astorga Leiva, F Plaza Parrochia… - 2016 - repositorio.uchile.cl
BACKGROUND/OBJECTIVES: A high percentage of women having polycystic ovarian
syndrome (PCOS) exhibit hyperinsulinemia and obesity. Transforming necrosis factor-alpha …