Radiomics and radiogenomics in gliomas: a contemporary update

G Singh, S Manjila, N Sakla, A True, AH Wardeh… - British journal of …, 2021 - nature.com
The natural history and treatment landscape of primary brain tumours are complicated by the
varied tumour behaviour of primary or secondary gliomas (high-grade transformation of low …

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

LS Hu, F D'Angelo, TM Weiskittel, FP Caruso… - Nature …, 2023 - nature.com
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing
(NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present …

Radiomics and radiogenomics in pediatric neuro-oncology: a review

R Madhogarhia, D Haldar, S Bagheri… - Neuro-Oncology …, 2022 - academic.oup.com
The current era of advanced computing has allowed for the development and
implementation of the field of radiomics. In pediatric neuro-oncology, radiomics has been …

FDA-approved machine learning algorithms in neuroradiology: a systematic review of the current evidence for approval

AG Yearley, CMW Goedmakers, A Panahi… - Artificial Intelligence in …, 2023 - Elsevier
Over the past decade, machine learning (ML) and artificial intelligence (AI) have become
increasingly prevalent in the medical field. In the United States, the Food and Drug …

An image-based modeling framework for predicting spatiotemporal brain cancer biology within individual patients

KM Bond, L Curtin, S Ranjbar, AE Afshari, LS Hu… - Frontiers in …, 2023 - frontiersin.org
Imaging is central to the clinical surveillance of brain tumors yet it provides limited insight
into a tumor's underlying biology. Machine learning and other mathematical modeling …

Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm

L Wang, H Wang, F D'Angelo, L Curtin, CP Sereduk… - PloS one, 2024 - journals.plos.org
Background and objective Glioblastoma (GBM) is one of the most aggressive and lethal
human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for …

Advanced MRI protocols to discriminate glioma from treatment effects: state of the art and future directions

DG Malik, TJ Rath, JC Urcuyo Acevedo… - Frontiers in …, 2022 - frontiersin.org
In the follow-up treatment of high-grade gliomas (HGGs), differentiating true tumor
progression from treatment-related effects, such as pseudoprogression and radiation …

Deep learning characterization of brain tumours with diffusion weighted imaging

C Meaney, S Das, E Colak, M Kohandel - Journal of Theoretical Biology, 2023 - Elsevier
Glioblastoma multiforme (GBM) is one of the most deadly forms of cancer. Methods of
characterizing these tumours are valuable for improving predictions of their progression and …

Dynamic contrast-enhanced MRI radiomics model predicts epidermal growth factor receptor amplification in glioblastoma, IDH-wildtype

B Sohn, K Park, SS Ahn, YW Park, SH Choi… - Journal of Neuro …, 2023 - Springer
Purpose To develop and validate a dynamic contrast-enhanced (DCE) MRI-based radiomics
model to predict epidermal growth factor receptor (EGFR) amplification in patients with …

Image-localized biopsy mapping of brain tumor heterogeneity: A single-center study protocol

JC Urcuyo, L Curtin, JM Langworthy, G De Leon… - PloS one, 2023 - journals.plos.org
Brain cancers pose a novel set of difficulties due to the limited accessibility of human brain
tumor tissue. For this reason, clinical decision-making relies heavily on MR imaging …