Harmony in transcripts: a systematic literature review of transcriptome-wide association studies
MA Mashhour, AH Kandil, M AbdElwahed… - Journal of Engineering …, 2024 - Springer
Transcriptome-wide association studies (TWAS) goal is to better understand the etiology of
diseases and develop preventative and therapeutic approaches by examining the …
diseases and develop preventative and therapeutic approaches by examining the …
Transcriptome analysis identifies genetic risk markers and explores the pathogenesis for inflammatory bowel disease
J Wang, M Sun, X Liu, Q Yan, Q Gao, K Ni… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is an incurable and disabling bowel disease driven by
multiple risk factors that severely limit patients' quality of life. We integrated the RNA …
multiple risk factors that severely limit patients' quality of life. We integrated the RNA …
Identification and validation of the diagnostic markers for inflammatory bowel disease by bioinformatics analysis and machine learning
Q Tang, X Shi, Y Xu, R Zhou, S Zhang, X Wang… - Biochemical …, 2024 - Springer
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract which is mediated by the inappropriate immune responses. This study was aimed to …
tract which is mediated by the inappropriate immune responses. This study was aimed to …
Polygenic risk and causal inference of psychiatric comorbidity in inflammatory bowel disease among patients with European ancestry
Background Approximately 40% of persons with inflammatory bowel disease (IBD)
experience psychiatric comorbidities (PC). Previous studies demonstrated the polygenetic …
experience psychiatric comorbidities (PC). Previous studies demonstrated the polygenetic …
Novel insight into the gene etiology of ulcerative colitis gained from transcriptome association study and single cell sequence analysis
J Jia, D Ren, K Yu, D Zhao, D Wang - 2024 - researchsquare.com
Background: Ulcerative colitis (UC) is a prevalent chronic gastrointestinal disease. Gene
plays an important role in UC pathogenesis. Therefore, we aim to identify UC susceptibility …
plays an important role in UC pathogenesis. Therefore, we aim to identify UC susceptibility …