Galectin-7 is a soluble unglycosylated lectin that is able to bind specifically to β-
galactosides. It has been described to be involved in apoptosis, proliferation and …

Galectins are small unglycosylated soluble lectins distributed both inside and outside the
cells. They share a conserved domain for the recognition of carbohydrates (CRD). Although …

Endocrine therapies for prostate cancer inhibit the androgen receptor (AR) transcription
factor. In most cases, AR activity resumes during therapy and drives progression to …

Aberrations in glycan and lectin expression and function represent one of the earliest
hallmarks of cancer. Among galectins, a conserved family of β-galactoside-binding lectins …

Galectins are commonly overexpressed in cancer cells and their expression pattern is often
associated with the aggressiveness and metastatic phenotype of the tumor. This study …

Non-melanoma skin cancer (NMSC) has risen dramatically as a result of chronic exposure
to sunlight ultraviolet (UV) radiation, climatic changes and clinical conditions associated with …

Background: Galectins (LGALS) are a family of carbohydrate-binding proteins, and LGALS
family members have shown prognostic roles in various types of cancers. However, the …

In accordance with the development of human technology, various medications have been
speedily developed in the current decade. While they have beneficial impact on various …

The role of glycan-binding proteins as an activator of immune regulatory receptors has
gained attention recently. We report that galectin 7 reduced CD4+ T cell percentage in both …

Lichen sclerosus is a chronic and inflammatory disease. Extensive studies have focused on
the epidermis, with the dermis or epidermis‑dermis receiving less attention. To investigate …