Ecology and genomics of Actinobacteria: new concepts for natural product discovery

DA van Bergeijk, BR Terlouw, MH Medema… - Nature Reviews …, 2020 - nature.com
Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Chemical ecology of antibiotic production by actinomycetes

A Van der Meij, SF Worsley… - FEMS microbiology …, 2017 - academic.oup.com
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Marine actinomycetes, new sources of biotechnological products

SV Jagannathan, EM Manemann, SE Rowe… - Marine Drugs, 2021 - mdpi.com
The Actinomycetales order is one of great genetic and functional diversity, including diversity
in the production of secondary metabolites which have uses in medical, environmental …

Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

[HTML][HTML] Antibiotics produced by Streptomyces

REL Procópio, IR Silva, MK Martins… - Brazilian Journal of …, 2012 - SciELO Brasil
Streptomyces is a genus of Gram-positive bacteria that grows in various environments, and
its shape resembles filamentous fungi. The morphological differentiation of Streptomyces …

Taxonomy, physiology, and natural products of Actinobacteria

EA Barka, P Vatsa, L Sanchez… - Microbiology and …, 2016 - Am Soc Microbiol
Actinobacteria are Gram-positive bacteria with high G+ C DNA content that constitute one of
the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and …

The Bacillus subtilis endospore: assembly and functions of the multilayered coat

PT McKenney, A Driks, P Eichenberger - Nature Reviews Microbiology, 2013 - nature.com
Sporulation in Bacillus subtilis involves an asymmetric cell division followed by
differentiation into two cell types, the endospore and the mother cell. The endospore coat is …

Anthracyclines: biosynthesis, engineering and clinical applications

MB Hulst, T Grocholski, JJC Neefjes… - Natural Product …, 2022 - pubs.rsc.org
Covering: January 1995 to June 2021 Anthracyclines are glycosylated microbial natural
products that harbour potent antiproliferative activities. Doxorubicin has been widely used as …

Staying in shape: the impact of cell shape on bacterial survival in diverse environments

DC Yang, KM Blair, NR Salama - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Bacteria display an abundance of cellular forms and can change shape during their life
cycle. Many plausible models regarding the functional significance of cell morphology have …

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era

HU Van Der Heul, BL Bilyk, KJ McDowall… - Natural product …, 2018 - pubs.rsc.org
Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …