Escherichia coli cells are primed for survival before lethal antibiotic stress

T Hossain, A Singh, NC Butzin - Microbiology Spectrum, 2023 - Am Soc Microbiol
Non-genetic factors can cause significant fluctuations in gene expression levels. Regardless
of growing in a stable environment, this fluctuation leads to cell-to-cell variability in an …

Proton motive force inhibitors are detrimental to methicillin-resistant staphylococcus aureus strains

SG Mohiuddin, S Ghosh, P Kavousi… - Microbiology …, 2022 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) strains are tolerant of conventional
antibiotics, making them extremely dangerous. Previous studies have shown the …

High-throughput screening of a promoter library reveals new Persister mechanisms in Escherichia Coli

SG Mohiuddin, A Massahi, MA Orman - Microbiology Spectrum, 2022 - Am Soc Microbiol
Persister cells are a small subpopulation of phenotypic variants that survive high
concentrations of bactericidal antibiotics. Their survival mechanisms are not heritable and …

Comprehensive metabolite profiling and therapeutic potential of black gram (Vigna mungo) pods: conversion of biowaste to wealth approach

M Arumugam, DB Manikandan, S Mohan… - Biomass Conversion …, 2023 - Springer
The risk faced by the drug-resistant pathogens, research, and development for viable
alternative medicine is gaining traction. This study aims to utilize agricultural waste …

Stimulating transcription in antibiotic-tolerant Escherichia coli sensitizes it to fluoroquinolone and nonfluoroquinolone topoisomerase inhibitors

TJ LaGree, BA Byrd, RM Quelle… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Antibiotic tolerant bacteria and persistent cells that remain alive after a course of antibiotic
treatment can foster the chronicity of infections and the development of antibiotic resistance …

lon Deletion Impairs Persister Cell Resuscitation in Escherichia coli

SG Mohiuddin, A Massahi, MA Orman - MBio, 2022 - Am Soc Microbiol
Bacterial persisters are nongrowing cells highly tolerant to bactericidal antibiotics. However,
this tolerance is reversible and not mediated by heritable genetic changes. Lon, an ATP …