Prospective applications of single-domain antibodies in biomedicine

SV Tillib - Molecular Biology, 2020 - Springer
Methods that utilize highly specific antibodies, anti-idiotypic antibodies, various recombinant
molecules with antibody properties and immunocorrection and immunoprophylaxis with the …

Immunomodulatory potential of anti-idiotypic antibodies for the treatment of autoimmune diseases

SY Pan, YC Chia, HR Yee, AY Fang Cheng… - Future science …, 2021 - Taylor & Francis
The immune system is a complex network of specialized cells and organs that recognises
and reacts against foreign pathogens while remaining unresponsive to host tissues. This …

Immunization with 674–685 fragment of SARS-Cov-2 spike protein induces neuroinflammation and impairs episodic memory of mice

O Lykhmus, O Kalashnyk, L Koval, O Krynina… - Biochemical and …, 2022 - Elsevier
COVID-19 is accompanied by strong inflammatory reaction and is often followed by long-
term cognitive disorders. The fragment 674–685 of SARS-Cov-2 spike protein was shown to …

A novel strategy for an anti-idiotype vaccine: nanobody mimicking neutralization epitope of porcine circovirus type 2

Y Deng, Y Sheng, G Zhang, Y Sun, L Wang… - Journal of …, 2024 - Am Soc Microbiol
Vaccination is the most effective method to protect humans and animals from diseases. Anti-
idiotype vaccines are safer due to their absence of pathogens. However, the commercial …

The role of α7 nicotinic acetylcholine receptors in post-acute sequelae of covid-19

M Skok - The International Journal of Biochemistry & Cell …, 2024 - Elsevier
Abstract Post-Acute Sequelae of COVID-19 or Long COVID becomes evident some weeks to
months following acute COVID-19. Symptoms include cognitive impairment and varying …

Idiotype/anti-idiotype antibodies: as a glorious savior in COVID-19 pandemics

A Naveed, D Naz, S Rahman - Translational Medicine Communications, 2021 - Springer
The idiotype network is experimentally modified to provide protective immunity against
various microbial pathogens. Both internal and non-internal image-idiotype antibodies can …

Anti-Idiotypic Nanobodies Mimicking an Epitope of the Needle Protein of the Chlamydial Type III Secretion System for Targeted Immune Stimulation

EA Koroleva, OS Goryainova, TI Ivanova… - International Journal of …, 2024 - mdpi.com
The development of new approaches and drugs for effective control of the chronic and
complicated forms of urogenital chlamydia caused by Chlamydia trachomatis, which is …

Autoimmunity and Diseases

AJ Alkhatib - The Role of Microbes in Autoimmune Diseases: New …, 2022 - Springer
This chapter introduces several diseases that can be mediated by autoimmunity including
diabetes, cancers, and others. Immunopathological details were explored. The author …

Anti-Idiotype Vaccine Provides Protective Immunity Against Vibrio Harveyi in Grouper (Epinephelus Coioides)

WL Huang, SC Chuang, CD Yang - Vaccines, 2019 - mdpi.com
Since anti-idiotype antibodies (anti-Id Abs) can display internal images similar to the
epitopes of the original antigens, we aimed to produce an effective vaccine based on anti-Id …

Development of Anti-idiotypic Monoclonal Antibody Mimicking SARS-CoV-2 Receptor Binding Domain

G Kılıç, E Demirkan, F Yücel - Molecular Biotechnology, 2024 - Springer
Using the hybridoma technique, we developed a panel of anti-idiotypic monoclonal
antibodies (aId-mAb) that mimic The Severe Acute Respiratory Syndrome Coronavirus 2 …