Designing synthetic microbial communities with the capacity to upcycle fermentation byproducts to increase production yields

R Rafieenia, C Klemm, P Hapeta, J Fu, MG García… - Trends in …, 2024 - cell.com
Microbial cell factories, which convert feedstocks into a product of value, have the potential
to help transition toward a bio-based economy with more sustainable ways to produce food …

Perspective on the development of synthetic microbial community (SynCom) biosensors

J Yuan, K Zhao, X Tan, R Xue, Y Zeng, C Ratti… - Trends in …, 2023 - cell.com
Synthetic microbial community (SynCom) biosensors are a promising technology for
detecting and responding to environmental cues and target molecules. SynCom biosensors …

A roadmap to establish a comprehensive platform for sustainable manufacturing of natural products in yeast

G Naseri - Nature Communications, 2023 - nature.com
Secondary natural products (NPs) are a rich source for drug discovery. However, the low
abundance of NPs makes their extraction from nature inefficient, while chemical synthesis is …

Microbial engineering strategies to utilize waste feedstock for sustainable bioproduction

N Aggarwal, HL Pham, B Ranjan, M Saini… - Nature Reviews …, 2024 - nature.com
The desire to move from a fossil fuel-based 'take–make–dispose'economy to a bio-based
circular economy has generated great interest in microbial metabolic engineering for its …

Assembly of functional microbial ecosystems: from molecular circuits to communities

S Wu, Y Zhou, L Dai, A Yang… - FEMS Microbiology …, 2024 - academic.oup.com
Microbes compete and cooperate with each other via a variety of chemicals and circuits.
Recently, to decipher, simulate, or reconstruct microbial communities, many researches …

Current insights into environmental acetochlor toxicity and remediation strategies

WJ Chen, SF Chen, H Song, Z Li, X Luo… - Environmental …, 2024 - Springer
Acetochlor is a selective pre-emergent herbicide that is widely used to control annual grass
and broadleaf weeds. However, due to its stable chemical structure, only a small portion of …

A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities

H Peng, APS Darlington, EJ South, HH Chen… - Nature …, 2024 - nature.com
Engineered microbial consortia often have enhanced system performance and robustness
compared with single-strain biomanufacturing production platforms. However, few tools are …

Identifying LasR Quorum Sensors with Improved Signal Specificity by Mapping the Sequence–Function Landscape

M Zeng, B Sarker, SN Rondthaler, V Vu… - ACS Synthetic …, 2024 - ACS Publications
Programmable intercellular signaling using components of naturally occurring quorum
sensing can allow for coordinated functions to be engineered in microbial consortia. LuxR …

Microbial Synthetic Epigenetic Tools Design and Applications

I Komera, X Chen, L Liu, C Gao - ACS Synthetic Biology, 2024 - ACS Publications
Microbial synthetic epigenetics offers significant opportunities for the design of synthetic
biology tools by leveraging reversible gene control mechanisms without altering DNA …

Cell-free systems: A synthetic biology tool for rapid prototyping in metabolic engineering

K Jeung, M Kim, E Jang, YJ Shon, GY Jung - Biotechnology Advances, 2025 - Elsevier
Microbial cell factories provide sustainable alternatives to petroleum-based chemical
production using cost-effective substrates. A deep understanding of their metabolism is …