Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

The concept of “network target” has ushered in a new era in the field of traditional Chinese
medicine (TCM). As a new research approach, network pharmacology is based on the …

Understanding the factors that affect water quality and the ecological services provided by
freshwater ecosystems is an urgent global environmental issue. Predicting how water quality …

Accumulating experimental evidence has indicated that long non-coding RNAs (lncRNAs)
are critical for the regulation of cellular biological processes implicated in many human …

Computational prediction of interactions between drugs and their target proteins is of great
importance for drug discovery and design. The difficulties of developing computational …

Background The identification of microRNA-disease associations is critical for
understanding the molecular mechanisms of diseases. However, experimental …

Stress is perhaps easiest to conceptualize as a process which allows an organism to
accommodate for the demands of its environment such that it can adapt to the prevailing set …

Abstract microRNAs (miRNAs) mutation and maladjustment are related to the occurrence
and development of human diseases. Studies on disease-associated miRNA have …

Many efforts are still devoted to the discovery of genes involved with specific phenotypes, in
particular, diseases. High‐throughput techniques are thus applied frequently to detect …

Accumulating evidence has demonstrated dysfunctions of long non-coding RNAs (lncRNAs)
are involved in various complex human diseases. However, even today, the relationships …