This article focuses on the production of chemokines by resident glial cells of the nervous
system. We described studies in two distinct categories of inflammation within the nervous …

In most regions of the central nervous system (CNS), the composition of the neuronal
microenvironment is maintained by virtue of particular blood–brain-barrier (BBB) …

Chemokines direct tissue invasion by specific leukocyte populations. Thus, chemokines may
play a role in multiple sclerosis (MS), an idiopathic disorder in which the central nervous …

Dynamic interplay between cytokines and chemokines directs trafficking of leukocyte
subpopulations to tissues in autoimmune inflammation. We have examined the role of IFN-γ …

Virus infection of host cells activates a set of cellular genes, including cytokines, IFNs, and
chemokines, involved in antiviral defense and immune activation. Previous studies …

Infection of C57BL/6 mice with mouse hepatitis virus (MHV) results in a demyelinating
encephalomyelitis characterized by mononuclear cell infiltration and white matter …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) and
is characterized by the destruction of myelin and axons leading to progressive disability …

Recent years have witnessed a remarkable growth in literature related to the biology and
treatment of multiple sclerosis (MS). The focus of this article is on aspects of the human …

Pro‐inflammatory CD4+ T‐cell‐mediated autoimmune diseases, such as multiple sclerosis
and type 1 diabetes, are hypothesized to be initiated and maintained by activated antigen …

Inflammatory cell recruitment is an important step in the pathogenesis of autoimmune
demyelinating diseases of the PNS. Chemokines might play a critical role in promoting …